解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Swertiamarin, a secoiridoid isolated from the ethyl acetate extract of Enicostemma axillare, was evaluated for antiedematogenic activity using carrageenan-, formalin-, and histamine-induced paw edema methods in rats. In the carrageenan-induced method, the percentages of edema inhibition obtained after 5 h induction we...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1088333
更新日期:2009-01-01 00:00:00
abstract::Averrhoa bilimbi Linn. fruit and its extracts were screened for antihypercholesterolemic activity using Triton-induced hypercholesterolemia in rats as a model. The fruit and its water extract, but not alcohol and hexane extracts, showed remarkable antihypercholesterolemic activity. An active fraction, which showed act...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1088361
更新日期:2009-01-01 00:00:00
abstract::An allergenic protein from tatary buckwheat seeds, designated TBt, was purified by salting out, anion exchange chromatography and size exclusion chromatography (SEC). Analysis by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and SEC showed that the allergenic protein was composed of two subunits...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1088319
更新日期:2008-12-01 00:00:00
abstract::A sensitive and rapid liquid chromatography-mass spectrometric method for the determination of ophiopogonin D in rat plasma was developed and validated. Chromatographic separation was performed on a C (18) column using a step gradient program with the mobile phase of 0.5 mmol/L ammonium chloride solution and acetonitr...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1088339
更新日期:2008-12-01 00:00:00
abstract::Thyme extract is known to posses spasmolytic effects on isolated trachea and to increase ciliary activity. A small part of this effect is mediated via beta (2) receptors, but other receptors are supposed to be involved. Endothelin has a pathophysiological impact in asthma with respect to hyper-reagibility and contract...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1081349
更新日期:2008-10-01 00:00:00
abstract::A systematic structure-activity relationship of 3beta-hydroxy-27- P- E-coumaroyloxyurs-12-en-28-oic acid ( 7), a triterpene ester isolated from UNCARIA RHYNCHOPHYLLA as a phospholipase Cgamma1 inhibitor, was undertaken with a view toward elucidating its chemical mode of action on PLCgamma1. Related derivatives and ana...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1081348
更新日期:2008-10-01 00:00:00
abstract::This perspective describes some commonly used animal models for the evaluation of potential chemopreventive agents in colon carcinogenesis. Special emphasis is given to the azoxymethane (AOM)/1,2-dimethylhydrazine (DMH) rat model and APCMIN mice, carrying a mutation in APC, a key gene in human carcinogenesis. In the A...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1074577
更新日期:2008-10-01 00:00:00
abstract::Phytochemical analysis of the leaves of BOLDOA PURPURASCENS Cav. led to isolation of four flavone glycosides, three of which are new compounds. Their structures have been determined by mass spectrometry and by 1 D and 2 D NMR analysis, i. e., 4',5-dihydroxy-6,7-methylenedioxyflavonol 3- O-alpha- L-rhamnopyranosyl-(1--...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1081332
更新日期:2008-10-01 00:00:00
abstract::Scientific achievements in the last two decades have revolutionized the treatment and prevention of breast cancer. This is mainly because of targeted therapies and a better understanding of the relationship between estrogen, its receptor, and breast cancer. One of these discoveries is the use of synthetic selective es...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0028-1088304
更新日期:2008-10-01 00:00:00
abstract::The high number of citations of the previous review on anti-HIV compounds from plants published in 1998 in Planta Medica indicates the importance of natural products research in the battle against HIV. Therefore, we have decided to write an update of our previous review paper, this time covering the time span 1998 - 2...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1081314
更新日期:2008-09-01 00:00:00
abstract::Two new triterpenoid saponins, along with five known ones, were isolated from the EtOH extract of the whole plants of Androsace umbellata. The structures of the new triterpenoid saponins were identified as 3- O-[ beta- D-xylopyranosyl-(1-->2)- beta- D-glucopyranosyl-(1-->4)-[ beta- D-glucopyranosyl-(1-->2)]- alpha- L-...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1081291
更新日期:2008-08-01 00:00:00
abstract::To provide a better understanding of the anti-complement activity of triterpenoids, seven unusual pentacyclic triterpenoids bearing a carboxyl group at C-27 were evaluated for their anticomplement activities against the classical pathway of the complement system. The triterpenoids were isolated from the whole plant of...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1074534
更新日期:2008-06-01 00:00:00
abstract::Novel therapies are needed to address the public health problem posed by methicillin-resistant STAPHYLOCOCCUS AUREUS (MRSA). In this study, we determined the effects of combinations of antibiotics and plant polyphenols against 20 clinical isolates of MRSA. The IN VITRO activities of 10 antibiotics and 15 natural polyp...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1074559
更新日期:2008-06-01 00:00:00
abstract::A novel bibenzyl, a new bibenzyl, two new phenanthrenes, and a new lignin glycoside, namely longicornuol A (1), 4-[2-(3-hdroxyphenol)-1-methoxyethyl]-2,6-dimethoxyphenol (2), 5-hydroxy-7-methoxy-9,10-dihydrophenanthrene-1,4-dione (3), 7-methoxy-9,10-dihydrophenanthrene-2,4,5-triol (4) and erythro-1-(4-O-beta-D-glucopy...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1074492
更新日期:2008-04-01 00:00:00
abstract::Three new compounds, namely, (+)-dihydrodehydrodiconiferyl alcohol 4- O- beta-(6''- O-galloyl)-glucopyranoside ( 1), 4,4'- O-dimethylellagic acid 3-(2''- O-acetyl)- alpha-rhamnopyranoside ( 2), and ethyl O- beta-(6'-galloyl)-glucopyranoside ( 3), together with eleven known ones, were isolated from the stem bark of Tre...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034361
更新日期:2008-03-01 00:00:00
abstract::Interleukin (IL)-5 plays an important role in the progression of allergic inflammation. Here, we have isolated 21alpha-methylmelianodiol and 21beta-methylmelianodiol from Poncirus trifoliata (L.) Raf., a plant of the Rutaceae family, as the inhibitors of IL-5-dependent growth of Y16 pro-B cells by bioassay-guided frac...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034329
更新日期:2008-03-01 00:00:00
abstract::Extracts of Viscum album L. produced by a specific homogenization procedure contain viscotoxins (VT) and liposome-like membrane vesicles, formed from cellular membranes. Interactions between these membrane structures and viscotoxins are characterized in this work. Binding properties of viscotoxins with mistletoe extra...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034282
更新日期:2008-02-01 00:00:00
abstract::Human immunodeficiency virus (HIV) infection can result in oxidative stress through production of reactive oxygen species (ROS). Simultaneously, oxidative stress is able to activate the replication of virus and lead to the apoptosis of T lymphocytes which is the defense of the immune function. Ampelopsin, belonging to...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034317
更新日期:2008-02-01 00:00:00
abstract::The solid dispersion of a poorly water-soluble Silybum marianum extract (SME) was prepared by a one-step fluid-bed coating technique depositing onto non-pareil pellets. In vitro evaluation indicated that this technique was highly efficient and reproducible producing pellets with acceptable appearance, flowability, fri...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034294
更新日期:2008-02-01 00:00:00
abstract::Poncirus trifoliata (Rutaceae) extracts have been known to possess anti-allergic, anti-inflammatory and antiviral activities. However, other biological activities, especially, the anticancer potential of extracts of P. trifoliata or its constituents, have not been fully investigated yet. In this study, we have evaluat...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034286
更新日期:2008-02-01 00:00:00
abstract::The dried rhizome of Panax notoginseng is a traditional Chinese herb extensively used for treatment of cardiovascular diseases and other ailments. Panax notoginseng saponins (PNS) are known as the major pharmacologically active constituents. The purpose of this study was to investigate the cardioprotective effects of ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034303
更新日期:2008-02-01 00:00:00
abstract::Embelia ribes Burm. f. (Myrsinaceae) is one of the important plants used in Indian traditional medicine. RAPD-PCR analysis was performed to obtain species-specific DNA fragments. A band of 906 bp that was specific to Embelia ribes irrespective of the geographical source was obtained using the random decamer primer OPF...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034279
更新日期:2008-02-01 00:00:00
abstract::The effects of four fractions, a hexane fraction, an ethyl acetate fraction, an N-butanol fraction and a water fraction, from a water extract of Herba Visci were investigated to find the fraction, in IN VITRO experiments, with the greatest ability to inhibit the formation of osteoclast-like multinucleated cells from m...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034283
更新日期:2008-02-01 00:00:00
abstract::DNA sequence analysis of the rDNA internal transcribed spacer 1 (ITS1) and TaqMan real-time polymerase chain reaction were exploited for their applications in the differentiation of the traditional chinese medicinal plants euphorbia humifusa and e. maculata from three related adulterants e. hypericifolia, E. atoto and...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034305
更新日期:2008-02-01 00:00:00
abstract::The antimycobacterial quinolones 1-methyl-2-undecyl-4-quinolone, dihydroevocarpine and evocarpine as well as the indoloquinazoline alkaloids rutaecarpine and evodiamine - all from the Chinese medicinal herb Evodia rutaecarpa - were tested in two in vitro assays, for cytotoxicity and interaction with p-glycoprotein (p-...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-993743
更新日期:2007-12-01 00:00:00
abstract::In this study the skin permeation and the topical anti-inflammatory properties of ginger extracts were investigated. A commercial ginger dry extract (DE) and a gingerols-enriched dry extract (EDE) were evaluated for their in vivo topical anti-inflammatory activity by inhibition of Croton oil-induced ear oedema in mice...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-993741
更新日期:2007-12-01 00:00:00
abstract::Propolis has been reported to display a broad spectrum of biological activities such as anticancer, antioxidant, anti-inflammatory, antibiotic and antifungal properties, among others. There is great interest not only in the determination of the chemical composition of propolis but also in the understanding of the mech...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-993737
更新日期:2007-12-01 00:00:00
abstract::A new activity of triterpenes and triterpenoid glycosides against phytovirus has been found. Based on the anti-TMV replication activity in vivo, 47 triterpenes and triterpenoid glycosides were screened through the leaf-disk method together with indirect ELISA. Structure-activity relationships were analyzed according t...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990263
更新日期:2007-11-01 00:00:00
abstract::Medicinal herbs are increasingly used in the search for safe and efficient drug candidates for hepatitis C virus infection. In this study, we have investigated the anti-HCV effect of compounds from Mori Cortex Radicis. During a screening for extracts with anti-HCV affinity from medicinal plants (173 species), the meth...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990249
更新日期:2007-11-01 00:00:00
abstract::This article outlines the development of a simple and specific analytical method for the quantitative determination of eight coumarin constituents from the methanolic extract of the roots of Angelica gigas. The coumarin constituents present in the roots of Angelica gigas were separated using an acetonitrile (0.1 % ace...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990260
更新日期:2007-11-01 00:00:00
abstract::Andrographolide (Andro) is a potentially anti-inflammatory diterpenoid lactone isolated from the traditional herbal medicine ANDROGRAPHIS PANICULATA, which has been effectively used for the treatment of infection, inflammation, cold, fever and diarrhea in China for centuries. In the current study, we found that Andro ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990230
更新日期:2007-10-01 00:00:00
abstract::Antroquinonol ( 1), an ubiquinone derivative, was isolated from the solid-state fermented mycelium of Antrodia camphorata (Polyporaceae, Aphyllophorales), a parasitic fungus indigenous to Taiwan. The structure of compound 1 was elucidated by the analysis of their spectroscopic data. Its cytotoxic activities were evalu...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990232
更新日期:2007-10-01 00:00:00
abstract::Stabilization of growth factors in a wound environment is critical to the wound healing process. Here we report on the stabilization of key growth factors by a unique plant cell wall biomaterial. MicroSheets are clear cell wall fragments isolated from the non-living water storage cells in the pulp or inner gel of Aloe...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990225
更新日期:2007-10-01 00:00:00
abstract::We identified eight diterpenes from Cryptomeria japonica (Taxodiaceae), which inhibit the activity of the androgen receptor (AR) in human prostate cancer (PCa) 22Rv1-derived 103E cells. The compounds 6,12-dihydroxyabieta-5,8,11,13-tetraen-7-one ( 2), sugiol ( 3), ferruginol ( 4), and 5-epixanthoperol ( 7) have near 10...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990233
更新日期:2007-10-01 00:00:00
abstract::Our investigations into the stability of tincture preparations of milk thistle fruit [ Silybum marianum L. Gaertn. (Asteraceae)] have led to the characterization of a new flavonolignan 4-(4-hydroxy-3-methoxyphenyl)-7-[(2 R,3 R)-3,5,7-trihydroxy-4-oxochroman-2-yl]-1-oxo-1,3,3a,4,5,7a-hexahydro-2-benzofuran-5-carboxylic...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-981595
更新日期:2007-09-01 00:00:00
abstract::Alpinia galanga, or galangal, has been a popular condiment used in Thai and Asian cuisine for many years. However, relatively little is known of the potential beneficial or adverse health effects of this spice. This study was conducted to analyze the capacity of galangal extract to induce cytotoxicity and DNA damage i...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-981542
更新日期:2007-07-01 00:00:00
abstract::Bioactivity-guided fractionation of Saururus chinensis (Saururaceae) using a lymphoproliferation assay led us to isolate 5 lignans (compounds 1 - 5). Compounds 1 - 5 were identified as sauchinone, (-)-saucerneol, saucerneol C, manassantin A, and manassantin B, respectively, by spectroscopic analyses. The immunosuppres...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-981525
更新日期:2007-06-01 00:00:00
abstract::Croton caudatus is an important species in Dai folk medicine. Some other Croton species, in particular, C. kongensis, C. cascarilloides, C. crassifolius, C. lachnocarpus and C. olivaceus are often marketed as C. caudatus, and thus, the therapeutic effects of C. caudatus are not achieved. The respective morphological f...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-967197
更新日期:2007-06-01 00:00:00
abstract::Bioassay-guided fractionation of the anti-HIV-1 active EtOAc extract from leaves and twigs of Ochna integerrima led to the isolation of five new flavonoid glycosides 1 - 5, five known flavonoids 6 - 10, and two known flavonoid glycosides 11 and 12. Structures were determined based on spectroscopic analyses. 6- gamma, ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-981538
更新日期:2007-06-01 00:00:00
abstract::Three new compounds, 15-acetoxy-12-hydroxy-16-methyl-labda-8(17),13E-diene (1), ent-labda-8(17),13-dien-15,16-olid-19-oic acid methyl ester (2), and 12-hydroxy-labda-8(17),13-dien-15,16-olide (3), together with two known compounds, 19-acetoxy-ent-labda-8(17),13-dien-15,16-olide (4), and 16-acetoxy-12,15-epoxy-15beta-h...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-967170
更新日期:2007-05-01 00:00:00